Acceptable Sway of Daytime Temps?

If my rH sways day to day depending on the humidity outdoors am I always fine to adjust my temps. to realign my VPD? How much fluctuation in temps is too much? Am I completely fine as long as my day temps don’t sway beyond 5F? (I am aware of the risk of mold/mildew, most concerned if quality will be effected)

Another question, during ripening (soil grow) if I am unable to mimic fall weather to induce senescense without sacrificing optimal VPD and I am forced to choose one or another should I mimic the fall weather (70f-75f, dry as possible) OR should I attempt to maintain my optimal VPD and sacrafice mimicking fall weather all together?

I think 5-10f swing from day to night is totally fine.